Pluss Advanced Technologies

Celsure® Boxes: Supply Chain Solution for Temperature-Sensitive Medical Supplies



Celsure® boxes deployed


increase in the production capacity for Celsure® boxes

Geographical Focus
  • PAN India

Samridh support

SAMRIDH provided financial support to PLUSS Advanced Technologies’ to double its manufacturing capacity of Celsure® boxes, from 3,000 to 6,000 packs per month. This expansion was crucial for meeting the heightened demand for supply chain solutions during the COVID-19 pandemic. It facilitated the distribution of temperature-sensitive medical supplies, such as COVID-19 test kits, drugs, and vaccines, to remote locations where maintaining appropriate cold-chain conditions is challenging. Furthermore, SAMRIDH’s support led to additional capital raise by PLUSS in the form of equity.

~65% of routine immunization vaccines are freeze sensitive.[1]

25% of vaccines in India wasted due to suboptimal cold chain practices.[2]

~$7,512,930 is the cost of vaccine wastage due to the ice-based cold chain system in rural India.[3]

During the second wave of the COVID-19 pandemic in India, the number of infected cases spiked exponentially, highlighting the urgent need for universal vaccination as the ultimate solution. While vaccines were manufactured at accelerated speeds, administering them to the eligible adult population across the country was an insurmountable challenge. Most COVID-19 vaccines in India require cold storage, and any lapse in temperature control during transport or storage can compromise their potency. Given India’s inadequate infrastructure to meet these requirements, there was an urgent need to strengthen India’s cold chain management to achieve the national goal of universal vaccine coverage.

PLUSS provides Celsure® boxes that maintain precise temperatures between 2 and 8°C, 15 and 25°C, and -20°C, for up to five days without electricity. These containers utilize ‘Phase Change Materials’ for thermal energy storage, maintaining the inside temperature at desired levels for up to 120 hours. The innovation enhances operational and cost efficiency in transporting temperature-sensitive products. Celsure® containers are utilized by pharmaceutical, diagnostics, and biotech companies to pack and transport drugs, vaccines, test kits, clinical trial samples and other products requiring a constant temperature to maintain efficacy. PLUSS’s Celsure® range of Temperature Controlled shipping solution for pharmaceutical received the Government of India’s Technology Day award for 2021.